Inhibitors Pharmaceutical Materials Cabozantinib Malate CAS 1140909-48-3

Product Name: Cabozantinib Malate
Synonyms: (2S)-2-Hydroxybutanedioic acid compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1);Cabozantinib (S)-malate;Cabozantinib L-Malate Salt;N-[4-[(6,7-DiMethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide (2S)-;Cabozantinib (S)-Malate(XL-184);Cabozantinib L-Malate;Cabozantinib Malate (XL184);XL-184 (Malate)
CAS: 1140909-48-3
MF: C32H30FN3O10
MW: 635.5931032
 
Cabozantinib Malate Usage And Synthesis
 
Chemical Properties Off-White Solid
Uses Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret Inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell a poptosis.
Uses XL184 (Cabozantinib, BMS-907351) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively.
Uses Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
 

Our advantage:

 
2,Our prices are the best because of the discounts that we give to all our buyers. We give very good discounts which makes our prices outstanding in the market.
3,Genuine and 100% Guarantee on all orders you place. We Have the Best you will come across Online. We have adequate stock, and can arrange the delivery within 24hours when receiving the payment. Tracking number would be informed quickly after shipment.
4,We have the best customer service and excellent shipment ability. Contact us to have a full list of our products and price list.
 

 
 

Product Name: Cabozantinib Malate
Synonyms: (2S)-2-Hydroxybutanedioic acid compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1);Cabozantinib (S)-malate;Cabozantinib L-Malate Salt;N-[4-[(6,7-DiMethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide (2S)-;Cabozantinib (S)-Malate(XL-184);Cabozantinib L-Malate;Cabozantinib Malate (XL184);XL-184 (Malate)
CAS: 1140909-48-3
MF: C32H30FN3O10
MW: 635.5931032
 
Cabozantinib Malate Usage And Synthesis
 
Chemical Properties Off-White Solid
Uses Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell a poptosis.
Uses XL184 (Cabozantinib, BMS-907351) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively.
Uses Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
 

Our advantage:

 
2,Our prices are the best because of the discounts that we give to all our buyers. We give very good discounts which makes our prices outstanding in the market.
3,Genuine and 100% Guarantee on all orders you place. We Have the Best you will come across Online. We have adequate stock, and can arrange the delivery within 24hours when receiving the payment. Tracking number would be informed quickly after shipment.
4,We have the best customer service and excellent shipment ability. Contact us to have a full list of our products and price list.
 

 
 

For Pesticide Intermediates series, we can supply many kinds of Pesticide intermediates with good quality, such as Fluorinated Pesticide Intermediates, Chlorine-Containing Pesticide Intermediates,Heterocyclic Intermediates, and so on.

We have our own production factories and lab. We can develop new product according to customer`s require, because we cooperate with several university, please believe that we have research advantage. Our factory is in chemical industry park, gets produce license from government, can supply product steadily.

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