- This article is taken "magic nitric oxide," a book, the author: Dr. Fei Lide Murad (USA), Dr. Chen Zhenxing 8NS China Feed Industry Information Network - based feed, animal husbandry services

In the 1980s, several scientists, such as Feilid Murad and Robert F. Fuchgoth, continued to explore and determine the role of nitric oxide (NO) as a signaling molecule in the cardiovascular system. Boarded the podium of the 1998 Nobel Prize in Physiology and Medicine. Dr. Murad is a lifelong emeritus professor at the University of Texas Medical School in Houston. The team discovered that NO can control blood pressure, regulate blood flow, get blood to the tissues, and supply oxygen and nutrients to the body. In fact, almost all organizations Can not do without NO. Dr. Chen Zhenxing is a famous doctor and doctor of medicine in China. He pointed out that 99.9% of human diseases are related to NO, because there is NO in the human body where there is blood. Obstruction of blood circulation naturally causes various diseases of the body. NO can regulate blood circulation and participate in physiological reactions of the body's central nervous system, immune system, urinary and reproductive systems. 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

At present, NO has been widely used in medicine, health care, and life in the world. The main physiological effects of NO are summarized as follows : 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

1. Regulate vascular tone: NO can reduce the response of arteries to non-adrenergic stimulation, cause vasodilation, and regulate vascular tone by regulating endothelial vasoconstriction and growth factor expression; 8NS China Feed Industry Information Network - based on feed, service Livestock

2, regulation of myocardial contractility: many experiments directly prove that NO has an inhibitory effect on myocardial contractile function; 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

3, regulate the antithrombotic effect of the endothelium: NO is an effective platelet inhibitor, endothelial damage promotes platelet adhesion and aggregation, NO can inhibit platelet reaction; 8NS China Feed Industry Information Network - based on feed, service animal husbandry

4. Regulate the interaction between neutrophils and endothelial cells and the permeability of blood vessels: NO in the body can inhibit the aggregation of various blood components and adhere to the vascular endothelium, and prevent arteries by interfering with the activity of leukocyte adhesion molecules or inhibiting their expression. The formation of atherosclerosis; 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

5, regulate the proliferation of cells: NO can inhibit the synthesis of nucleic acids by inactivating the interaction between the active site on the ribonucleoside reductase and tyrosyl; through the interaction with the cytochrome hemoglobin Affects electron transfer, thereby inhibiting cell proliferation. 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

In a mammalian body, arginine synthesizes NO under the action of nitric oxide synthase, and simultaneously produces citrulline. NO diffuses through endothelial cells into surrounding smooth muscle cells, activates guanylate cyclase, and produces cyclic guanosine monophosphate, resulting in smooth muscle relaxation. This is also one of the great significance of arginine as a functional amino acid in recent years as a research hotspot by many scholars. As a substitute for the endogenous arginine synthesis, NCG can also promote the healthy growth of animals by promoting the synthesis of arginine and increasing the content of NO in the body. 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

Attached to the author of the book, Dr. Feilid Mullard's personal profile: 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

Honorary Professor of Life Sciences at the University of Texas Medical School in the United States; Albert Lasker Foundation Medicine Award in 1996; Academician of the National Academy of Sciences in 1997; Nobel Prize in Physiology and Medicine in 1998; The American Heart Association's Ciba Award; in 1998, he became a Fellow of the National Academy of Medical Sciences; in 2000, he received the Baxter Award from the American Medical Association; in 2007, he was elected a foreign academician of the Chinese Academy of Sciences. In addition, he has written and co-authored 334 medical science books. 8NS China Feed Industry Information Network - based on feed, serving animal husbandry

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