Capillary electrophoresis electrochemiluminescence detector was successfully developed

According to reports, electrochemiluminescence detection is a new detection method in capillary electrophoresis analysis developed in recent years. It combines capillary separation technology with electrochemiluminescence detection in clinical analysis and medicine, virus, immunity, etc. Scientific experiments will greatly simplify the technical difficulty of analysis and improve the accuracy of analysis. At present, there are no reports on electrochemiluminescence detection instruments in the world, and there are few reports on related application studies and effective immobilization of electrochemiluminescent reagents on the electrode surface.

According to the plan of the “National Science and Technology Research and Development” project of the “Tenth Five-Year Plan”, the institute undertook the research and development task of “Capillary Electrophoresis Electrochemiluminescence Detector” in December 2001. They and Xi Anrui The company has worked closely together for a year and a half to solve the problem of the design of the capillary electrophoresis separation unit in the instrument development, the integration of the electrochemical unit and the luminescence detection unit, and the electrochemical detection pool in which the separation capillary and the detector are conveniently installed together. Key technologies such as design and device assembly have successfully developed a capillary electrophoresis electrochemiluminescence detector that combines capillary electrophoresis separation and electrochemiluminescence detection. The current of the instrument changes with the potential change, the response speed, sensitivity and separation efficiency of the electrochemical control unit are effectively improved, and the CE/ECL online separation and real-time detection are realized. The capillary electrophoresis system, electrochemiluminescence system and its interface technology of the instrument have functions such as separate or combined use.

î ‹î ‹This kind of electrochemical analytical instrument can be used for the detection and analysis of drugs, amino acids, peptides, proteins and nucleic acids, and can be applied to the study of protein-drug and nucleic acid interactions. It has more in biochemistry, medicine, clinical and immune. Broad market prospects. At the same time, it greatly reduces the cost compared to the imported "capillary electrophoresis laser-induced fluorescence analyzer" commonly used in related fields. At present, the instrument has been applied to scientific analysis of medicine, medicine and other aspects.